Table 1.

Results of the pooled and subgroup analyses for the ADRB2 rs1042713 polymorphism and asthma risk

Variable	n	Case/Control	Dominant model comparison			Recessive model comparison			Homozygote genotype comparison			Allelic comparison			Frequency of minor allele (A/(A + G))
			OR[95%CI]	P(Z)	I2	OR[95%CI]	P(Z)	I2	OR[95%CI]	P(Z)	I2	OR[95%CI]	P(Z)	I2	Case	Control
Total	71	12,070/21669	1.08 [0.97, 1.21]	0.165	68%	1.05 [0.94, 1.18]	0.387	70%	1.10 [0.95, 1.27]	0.201	70%	1.02 [0.95, 1.10]	0.591	74%	0.494	0.443
Adult	36	6984/15697	1.12 [0.97, 1.28]	0.122	62%	1.05 [0.92, 1.19]	0.447	58%	1.12 [0.96, 1.32]	0.160	56%	1.06 [0.98, 1.15]	0.131	56%	0.485	0.430
Children	26	4539/5320	1.13 [0.93, 1.38]	0.210	72%	1.07 [0.85, 1.35]	0.570	79%	1.13 [0.85, 1.51]	0.400	79%	1.00 [0.85, 1.17]	0.976	84%	0.510	0.478
East-Asian	36	6343/6291	1.00 [0.87, 1.16]	0.966	63%	1.04 [0.87, 1.26]	0.645	71%	1.03 [0.84, 1.26]	0.801	67%	1.02 [0.93, 1.13]	0.677	69%	0.539	0.533
Indian	5	1190/1241	0.72 [0.59, 0.87]	0.001	25%	0.91 [0.69, 1.19]	0.480	54%	0.72 [0.51, 1.03]	0.070	53%	0.84 [0.69, 1.02]	0.073	60%	0.477	0.437
Arab	2	307/361	1.75 [1.14, 2.70]	0.011	0%	1.17 [0.59, 2.30]	0.654	69%	1.88 [1.17, 3.02]	0.009	35%	0.83 [0.34, 2.02]	0.165	51%	0.360	0.436
Hispanic-Latinos	5	1026/1412	1.68 [1.10, 2.55]	0.016	77%	1.64 [0.86, 3.14]	0.133	90%	2.09 [0.98, 4.45]	0.055	64%	0.99 [0.60, 1.63]	0.970	94%	0.464	0.481
non-Hispanic Blacks	5	671/556	1.55 [0.70, 3.42]	0.282	80%	1.22 [0.68, 2.19]	0.498	52%	1.40 [0.64, 3.06]	0.401	64%	0.70 [0.55, 0.89]	0.529	85%	0.529	0.532
Caucasian	16	2892/11950	1.05 [0.87, 1.25]	0.620	36%	0.96 [0.83, 1.11]	0.541	35%	1.01 [0.87, 1.16]	0.946	32%	0.99 [0.89, 1.10]	0.847	46%	0.430	0.389
HWE(P > 0.05)	49	9752/19296	0.99 [0.87, 1.13]	0.890	70%	0.97 [0.85, 1.10]	0.598	73%	0.98 [0.81, 1.16]	0.716	76%	0.98 [0.90, 1.07]	0.653	78%	0.486	0.431
HWE(P < 0.05)	18	2366/2320	1.22 [0.96, 1.55]	0.240	55%	1.17 [0.94, 1.44]	0.164	50%	1.17 [0.99, 1.38]	0.055	29%	1.15 [1.01, 1.30]	0.031	48%	0.520	0.541