Table 2.

Results of the pooled and subgroup analyses for the ADRB2 rs1042714 polymorphism and asthma risk

Variable	n	Case/Control	Dominant model comparison			Recessive model comparison			Homozygote genotype comparison			Allelic comparison			Frequence of minor allele (G/(G + C))
			OR[95%CI]	P(Z)	I2	OR[95%CI]	P(Z)	I2	OR[95%CI]	P(Z)	I2	OR[95%CI]	P(Z)	I2	Case	Control
Total	52	8242/16832	0.92 [0.83, 1.02]	0.097	45%	0.83 [0.70, 0.98]	0.032	44%	0.84 [0.72, 0.98]	0.028	25%	0.91 [0.83, 0.99]	0.029	59%	0.242	0.348
Adult	28	5022/13609	0.89 [0.77, 1.02]	0.101	55%	0.94 [0.83, 1.07]	0.372	6%	0.94 [0.81, 1.08]	0.371	0%	0.92 [0.83, 1.02]	0.095	52%	0.246	0.371
Children	18	2498/2510	0.97 [0.81, 1.16]	0.706	36%	0.59 [0.39, 0.88]	0.009	58%	0.63 [0.43, 0.92]	0.016	46%	0.86 [0.69, 1.07]	0.169	73%	0.205	0.234
East-Asian	27	4555/4217	0.94 [0.85, 1.04]	0.249	20%	0.81 [0.65, 1.01]	0.057	0%	0.82 [0.66, 1.03]	0.090	0%	0.93 [0.85, 1.01]	0.085	25%	0.164	0.161
Indian	3	672/687	0.85 [0.68, 1.07]	0.160	18%	1.04 [0.70, 1.54]	0.862	0%	0.95 [0.63, 1.43]	0.806	0%	0.91 [0.76, 1.09]	0.294	0%	0.234	0.250
Arab	2	137/196	0.98 [0.63, 1.51]	0.249	0%	1.14 [0.49, 2.61]	0.764	0%	1.11 [0.47, 2.60]	0.810	0%	1.01 [0.71, 1.43]	0.972	0%	0.270	0.273
Hispanic-Latinos	4	605/982	0.67 [0.41, 1.10]	0.108	75%	0.54 [0.13, 2.25]	0.394	90%	0.54 [0.18, 1.64]	0.276	82%	0.61 [0.33, 1.15]	0.129	91%	0.202	0.277
non-Hispanic Blacks	2	194/162	1.06 [0.53, 2.09]	0.875	58%	0.88 [0.40, 1.94]	0.758	0%	0.94 [0.41, 2.12]	0.876	0%	1.03 [0.74, 1.45]	0.845	41%	0.309	0.290
Caucasian	14	2079/10588	0.98 [0.81, 1.19]	0.840	51%	0.90 [0.78, 1.03]	0.126	29%	0.92 [0.79, 1.08]	0.319	11%	0.94 [0.82, 1.07]	0.338	50%	0.418	0.437
HWE(P > 0.05)	35	5552/14306	0.89 [0.80, 0.99]	0.034	32%	0.94 [0.83, 1.06]	0.299	0%	0.94 [0.81, 1.08]	0.358	0%	0.91 [0.84, 0.99]	0.021	28%	0.258	0.366
HWE(P < 0.05)	16	2478/2474	0.95 [0.77, 1.17]	0.637	59%	0.70 [0.47, 1.06]	0.089	69%	0.73 [0.51, 1.05]	0.088	58%	0.87 [0.70, 1.09]	0.239	79%	0.221	0.248