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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Nat Genet. 2019 Jan 7;51(3):404–413. doi: 10.1038/s41588-018-0311-9

Figure 2. GWAS meta-analysis for AD risk (N=455,258).

Figure 2.

Manhattan plot displays all associations per variant ordered according to their genomic position on the x-axis and showing the strength of the association with the −log10 transformed P-values on the y-axis. The y-axis is limited to enable visualization of non-APOE loci. For the Phase 3 meta-analysis, the original −log10 P-value for the APOE locus is 276.