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. 2019 Nov;29(11):1805–1815. doi: 10.1101/gr.249805.119

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© 2019 Ren et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 5. — Correlation analyses between evolutionary constraint and expression polymorphism. (A–C) Correlation analyses were performed between K_a/K_s values in parents and relevant log₂ |TC/BSB| of parents (red) and hybrids (blue) in cis-regulatory genes (17 shared genes in BT). The correlation coefficient between K_a/K_s values and relevant log₂ |TC/BSB| in parents was 0.5635 (P-values < 0.05, Pearson correlation coefficient). The correlation coefficients between K_a/K_s values in parents and relevant log₂ |TC/BSB| in hybrids are listed in the graph. (D) The log₂ |TC/BSB| values of the parents were determined in conserved genes (1055 in BTF₁, 912 in BTF₂, 966 in BTF₃, 1194 in TBF₁, 1045 in TBF₂, and 803 in TBF₃). (****) P < 0.0001 for Spearman's rank correlation coefficient; (**) P < 0.001. (E) The log₂ |TC/BSB| values of the hybrids were determined in “cis + trans” (from 565 to 1488 genes in all samples) and “cis × trans” genes (from 643 to 1504 genes in all samples) (all P < 0.0001, Spearman's rank correlation coefficient).