Table 2. Comparative MIC90s of quinolones. The potency of the drugs presented in MIC90 (mg L–1) of each drug on different Gram-negative strains and Gram-positive strains32–49 .
| MIC90 (mg L–1) | ||||||||||
| Gram-negative pathogens |
Gram-positive pathogens |
|||||||||
| E. coli | P. aeruginosa | Klebsiella spp. | B. fragilis | Haemophilus influenzae | S. aureus | S. pneumoniae | Group A Streptococci | Enterococcus spp. | Clostridium perfringens | |
| Nalidixic acid | 8 | >64 | 16 | >64 | 2 | >64 | >64 | >64 | >64 | >64 |
| Enoxacin | 0.25 | >64 | 2 | >64 | 0.12 | 2 | 64 | >64 | 8 | >64 |
| Norfloxacin | 0.12 | 2 | 0.5 | >64 | 0.06 | 1 | 16 | 4 | 4 | ND |
| Ciprofloxacin | 0.03 | 1 | 0.25 | 16 | 0.03 | 1 | 2 | 1 | 4 | 0.5 |
| Ofloxacin | 0.12 | 4 | 0.5 | 16 | 0.03 | 0.5 | 2 | 2 | 2 | 1 |
| Lomefloxacin | 0.06 | 2 | 0.25 | ND | 0.06 | 2 | 4 | 4 | 4 | ND |
| Sparfloxacin | 0.06 | 4 | 0.5 | 4 | 0.03 | 0.12 | 0.5 | 1 | 2 | 0.25 |
| Grepafloxacin | 0.06 | 8 | 0.12 | 8 | 0.01 | 0.12 | 0.25 | 1 | 4 | 1 |
| Clinafloxacin | 0.01 | 0.5 | 0.03 | 0.25 | 0.01 | 0.06 | 0.12 | 0.06 | 0.25 | 0.12 |
| Gatifloxacin | 0.06 | 4 | 0.25 | 1 | 0.03 | 0.25 | 0.25 | 0.25 | 1 | 0.5 |
| Moxifloxacin | 0.06 | 8 | 0.12 | 1 | 0.06 | 0.06 | 0.12 | 0.25 | 2 | 0.25 |
| Gemifloxacin | 0.03 | 4 | 0.25 | ND | 0.06 | 0.06 | 0.03 | 0.06 | 4 | ND |
| Trovafloxacin | 0.06 | 1 | 0.25 | 0.25 | 0.01 | 0.03 | 0.12 | 0.25 | 1 | 0.25 |
| Garenoxacin | 0.06 | 16 | 0.5 | 1 | 0.03 | 0.03 | 0.12 | 0.25 | 0.5 | 0.25 |