Table 1.
Baseline characteristics
| CAD group (n = 60) | CAD + ICVE group (n = 60) | P‐value | |
|---|---|---|---|
| Age (years ± SD)a | 67 ± 9 | 66 ± 9 | .49 |
| Male (%)a | 70 | 71 | .86 |
| AMI (%)a | 71.7 | 69.8 | .17 |
| Time since ACS (years ± SD)a | 5.6 ± 2.7 | 5.0 ± 2.7 | .20 |
| BMI (kg/m2 ± SD) | 27.45 ± 4.45 | 27.84 ± 5.64 | .85 |
| SBP (mmHg ± SD) | 123.62 ± 16.61 | 135.48 ± 19.22 | .01 |
| DBP (mmHg ± SD) | 75.75 ± 9.3 | 77.39 ± 10.92 | .30 |
| Diabetes (%) | 45 | 49 | .51 |
| Hypertension (%) | 85 | 93 | .48 |
| Hypercholesterolemia (%) | 80 | 69.8 | .14 |
| Current smoker (%) | 5.71 | 5.71 | 1.00 |
| Atrial fibrillation (%) | 2.9 | 7.1 | .17 |
| PCI (%) | 31.43 | 31.43 | 1.00 |
| Medications | |||
| Statin (%) | 95 | 95.2 | .95 |
| Antihypertensive medications (n ± SD) | 2.23 ± 1.06 | 2.89 ± 1.1 | .08 |
| ACE inhibitor (%) | 57.14 | 54.29 | .74 |
| ARB (%) | 15 | 27 | .12 |
| Calcium channel blocker (%) | 20 | 44.4 | .004 |
| Diuretic (%) | 35 | 42.9 | .46 |
| Beta blocker (%) | 78.3 | 88.9 | .14 |
| Oral hypoglycemic medication (%) | 45 | 41.3 | .71 |
| Insulin (%) | 16.7 | 9.5 | .29 |
| Oral anticoagulant (%) | 3.4 | 7.9 | .16 |
| Metabolic and inflammatory tests | |||
| Total cholesterol (mg/dL) | 166 ± 38 | 163 ± 39 | .65 |
| LDL‐C (mg/dL) | 93 ± 32 | 92 ± 30 | .87 |
| HDL‐C (mg/dL) | 44 ± 10 | 43 ± 13 | .66 |
| Triglyceride (mg/dL) | 144 ± 96 | 133 ± 60 | .36 |
| BUN (mg/dL) | 41.46 ± 15.17 | 44.26 ± 14.03 | .26 |
| GFR (mL/min/1.73 m2) | 68.63 ± 22.1 | 65.5 ± 22.23 | .28 |
| HBA1c (%) | 7.17 ± 2.27 | 7.66 ± 9.2 | .68 |
| Lipoprotein(a) (mg/dL) | 45 ± 45 | 47 ± 44 | .81 |
| us‐CRP (mg/dL) | 3.55 ± 4.32 | 6.48 ± 9.26 | .13 |
a
Prespecified matched variables.
Abbreviations: ACE, angiotensin converting enzyme; ACS, acute coronary syndromes; AMI, acute myocardial infarct; ARB, angiotensin receptor blocker; BMI, body mass index; BUN, blood urea nitrogen; DBP, diastolic blood pressure; GFR, glomerular filtration rate; HBA1c, glycated hemoglobin; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein‐cholesterol; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; us‐CRP, ultrasensitive C‐reactive protein.