Table 2.
Comparison of demographic and clinical characteristics between KTx patients with and without cognitive impairment.
| Patient characteristics | All N = 583 (100%)a |
DemTect <13 N = 91 (15.6%)b |
DemTect ≥ 13 N = 492 |
Statistics χ2 test, Mann-Whitney U test |
|---|---|---|---|---|
| Age (years), mean (SD) | 52.11 (14.25) | 55.32 (13.69) | 51.46 (14.23) | Z = −2.254, P = 0.024 |
| Female gender | 239 (41%) | 25 (27.5%) | 214 (43.5%) | χ 2 = 8.151 ( df = 1), P = 0.004 |
| ≥12 years school attendance (n = 552) | 151 (27.4%) | 12 (14.5%) | 139 (29.6%) | χ 2 = 8.177 ( df = 1), P = 0.004 |
| Hypertension | 501 (85.9%) | 86 (94.5%) | 415 (84.3%) | χ 2 = 6.553 ( df = 1), P = 0.010 |
| Renal anemia | 165 (28.3%) | 22 (13.3%) | 143 (86.7%) | χ2 = .905 (df = 1), P = 0.342 |
| Diabetes mellitus (1,2, and NODAT) | 101 (17.4%) | 20 (24.2%) | 81 (16.5%) | χ2 = 1.608 (df = 1), P = 0.205 |
| eGFR (ml/min/1.73 m 2 ), mean (SD) | 45.75 (18.44) | 40.46 (19.05) | 46.73 (18.18) | Z = −3.553, P = 0.001 |
| Creatinine (mg/dl), mean (SD) | 1.77 (0.69) | 2.04 (0.79) | 1.73 (0.67) | Z = −3.884, P = 0.001 |
| eGFR < 30 ml/min/1.73 m 2 | 120 (20.6%) | 29 (31.9%) | 91 (18.5%) | χ 2 = 8.401 ( df = 1), P = 0.004 |
| Living donation | 185 (29.9%) | 20 (22.0%) | 157 (31.9%) | χ2 = 3.583 (df = 1), P = 0.058 |
| Time since KT (months), mean (SD) | 66.06 (68.58) | 69.00 (76.4) | 65.5 (67.11) | Z = −0.161, P = 0.872 |
| Time on dialysis (months), mean (SD) | 60.25 (49.60) | 62.48 (44.33) | 59.84 (50.54 | Z = −0.815, P = 0.415 |
| MARS-D score (adherence), mean (SD) | 24.35 (1.33) | 24.34 (0.96) | 24.35 (1.38) | Z = −0.665, P = 0.506 |
| HADS Anxiety score, mean (SD) | 5.13 (3.92) | 5.18 (4.29) | 5.13 (3.86) | Z = −0.255, P = 0.799 |
| HADS Depression score, mean (SD) | 4.35 (4.00) | 4.85 (4.69) | 4.25 (3.87) | Z = −0.675, P = 0.500 |
| Subjective change of cognitive functioning (n = 574) | ||||
| Worse | 133 (23.2%) | 26 (28.9%) | 107 (22.1%) | χ 2 = 6.889 ( df = 2), P = 0.032 |
| Improved | 61 (10.6%) | 3 (3.3%) | 58 (12.0%) | |
| No change | 380 (66.2%) | 61 (67.8%) | 319 (65.9%) | |
| BMI ≥30 kg/m 2 (n = 425) | 75 (17.6%) | 19 (29.7%) | 56 (15.5%) | χ 2 = 7.516 ( df = 1), P = 0.006 |
aPercent of all participants, bpercent of the demographic variable or clinical characteristic.
P < 0.05 was considered statistically significant, DemTect <13 = patients with cognitive impairment, DemTect ≥13 = patients without cognitive impairment; statistically significant results (P < 0.05) are shown in boldface. The significance of bolded texts is p < 0.05 as suggested.