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Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
Graphical illustration of the biasing effect of controlling for LTLb in analyses of ΔLTL and LTLfu. This figure is based on simulated data and exaggerates the true difference in LTL between smokers and non-smokers. See text for explanation.