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. Author manuscript; available in PMC: 2019 Nov 7.
Published in final edited form as: Pediatr Neurol. 2019 Mar 13;96:58–63. doi: 10.1016/j.pediatrneurol.2019.03.003

TABLE 1.

Child and Parental Characteristics by Genotype

NMI
(n = 16)		 TSC1
(n = 13)		 TSC2
(n = 63)		 P
Value *
Child’s sex. n (%) 0.14
 Female 7 (43.3) 4 (30.8) 37 (58.7)
 Male 9 (56.2) 9 (69.2) 26 (41.3)
Child ethnicity, n (%) 0.73
 Hispanic 2 (12.5) 3 (23.1) 14 (22.2)
 Non-Hispanic 14 (87.5) 10 (76.9) 49 (77.8)
Term Birth, n (%) 0.06
 No 1 (6.2) 2 (15.4) 1 (1.6)
 Yes 15 (93.8) 11 (84.6) 62 (98.4)
Seizures, n (%) <0.001
 No 5 (31.2) 10 (76.9) 9 (14.3)
 Yes 11 (68.8) 3 (23.1) 54 (85.7)
Maternal age at birth, mean (S.D.) years 34.4 (4.3) 31.8 (6.1) 30.8 (5.1) 0.02
Paternal age at birth, mean (S.D.) years 36.8 (5.8) 34.5 (4.5) 33.0 (6.8) 0.06

Abbreviation:

NMI = No mutation identified.

Bold values indicate significance.

*

For sex, the P value is derived from chi-squared test. For other categorical variables. P values were derived from Fisher’s exact test, and for continuous variables P values were derived from the Kruskal-Wallis rank sum test. The P value is representative of the difference across the three groups.