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. 2019 Nov 7;14(11):e0224132. doi: 10.1371/journal.pone.0224132

Fig 5. Death of control, FRDA and FAD patient cells induced by bixafen.

Fig 5

A, Control cells were allowed to grow (n = 3) in either GlucoMax or MitoMax culture medium, which are permissive or nonpermissive for defective mitochondria (see Table 2), respectively, in the absence or presence of 0.5 μM or 1 μM bixafen. A similar experiment was carried out on fibroblasts from a Friedreich ataxia patient (FRDA fibroblasts) (B) and from a patient suffering from familial Alzheimer’s Disease (C). Culture media were not changed for the duration of the experiment (n = 3).