Table 2. Muscle oxidative stress markers determined pre and 0, 2, and 6 hours after acute exercise in the control (C) and creatine-supplemented (Cr) groups.
| Pre | 0 hour | 2 hours | 6 hours | ||
|---|---|---|---|---|---|
| MDA (µmol/g tissue) | C | 0.16 ± 0.02 | 0.13 ± 0.03 | 0.12 ± 0.03 | 0.15 ± 0.04 |
| Cr | 0.17 ± 0.02 | 0.14 ± 0.02 | 0.16 ± 0.03 | 0.14 ± 0.02 | |
| Lipid hydroperoxide (µmol/g tissue) | C | 23 ± 2.0a | 32.8 ± 3.4b | 49 ± 4.6c | 26.2 ± 2.8a |
| Cr | 22.9 ± 2.8a | 36.8 ± 4.5b | 44.8 ± 5.2c | 22.1 ± 3.8a | |
| AOPP (µmol/g tissue) | C | 0.62 ± 0.12a | 0.84 ± 0.14b | 0.65 ± 0.11a | 0.34 ± 0.07c |
| Cr | 0.38 ± 0.10*a | 0.63 ± 0.11*b | 0.65 ± 0.08b | 0.50 ± 0.18ab | |
| GSH (mmol/g tissue) | C | 3.2 ± 0.7a | 2.7 ± 0.4ab | 2.4 ± 0.3b | 2.2 ± 0.3b |
| Cr | 3.7 ± 0.6a | 3.2 ± 0.6ab | 3..0 ± 0.4b | 2.8 ± 0.2b | |
| GSH/GSSG | C | 7.1 ± 0.7a | 5.4 ± 1.0ab | 5.0 ± 0.4a | 4.6 ± 0.6a |
| Cr | 7.3 ± 0.8a | 5.1 ± 0.8b | 5.3 ± 0.5b | 4.7 ± 0.4b |
Values are mean ± SEM, n = 8.
abcMeans in a row followed by different letters were significantly different.
*Significant difference in relation to the control at the same time of euthanasia (P < 0.05 by linear mixed effects model).