Figure 1.

EMS suppresses ox-LDL-induced oxidative burst in peritoneal macrophages. EMS (1.5% in PBS; 1 ml; i.p.) was administrated daily for 3 days, using PBS as a vehicle control. On the 5th day, peritoneal macrophages were collected, washed in PBS, and activated by exposure to 100 µg/ml ox-LDL for 10 minutes. The resulting oxidative burst was analyzed by exposure to 10 µM DHR-123 using FACS. Values from three independent experiments are expressed as means ± SD. The ox-LDL in PBS group significantly differed from the control (PBS only) group (*P < 0.05), whereas the EMS + ox-LDL group did not (n = 15).