Table 2.

Mean plasma levels of oxidative stress biomarkers in control subjects and AAA patients classified according to the size of aneurysm (cutoff 50 mm)

		Control group	AAA ≤50 mm	AAA >50 mm
Variable	Reference values	(n = 18)	(n = 15)	(n = 12)	P-value**
Vitamin C (μg/ml)	6.2–18.8	10.9 ± 3.85	9.15 ± 2.73	7.35 ± 3.16	0.011
α-Tocopherol (μg/ml)	8.6–19.2	14.5 ± 3.34	12.4 ± 3.14	11.6 ± 2.91	0.016
γ-Tocopherol (μg/ml)	0.28–2.42	0.81 ± 0.38	0.92 ± 0.49	0.66 ± 0.29	0.50
Cholesterol (g/l)	1.2–1.9	2.04 ± 0.35	1.79 ± 0.54	1.62 ± 0.46	0.020
α-Tocopherol /cholesterol (mg/g)	4.4–7	7.16 ± 1.44	7.10 ± 1.31	7.38 ± 1.64	0.71
β-Carotene (mg/l)	0.05–0.68	0.29 ± 0.17	0.20 ± 0.18	0.11 ± 0.054	0.0096
Thiol proteins (μM)	310–523	311 ± 38	337 ± 45.7	312 ± 41.0	0.48
Ubiquinone (mg/l)	0.3–1.39	0.84 ± 0.32	0.70 ± 0.23	0.57 ± 0.21	0.014
Copper (mg/l)	0.8–1.20	0.88 ± 0.12	0.90 ± 0.26	0.90 ± 0.32	0.79
Zinc (mg/l)	0.7–1.20	0.79 ± 0.14	0.73 ± 0.10	0.63 ± 0.13	0.0035
Copper/zinc ratio	1–1.17	1.14 ± 0.21	1.24 ± 0.38	1.43 ± 0.42	0.046
Selenium (μg/l)	94–130	92.7 ± 16.4	83.8 ± 18.3	70.4 ± 21.0	0.0038
Lipid peroxides (μM)*	0–432	520 ± 228	574 ± 360	563 ± 307	0.82
Oxidized LDL (ng/ml)*	0–500	756 ± 964	205 ± 244	264 ± 220	0.062
Antibodies against oxidized LDL (UI/l)*	200–600	263 ± 282	255 ± 308	148 ± 87.5	0.32
Isoprostanes (ng/ml)	NA	1.01 ± 0.66	1.19 ± 0.64	1.68 ± 0.89	0.052
Paraoxonase (ng/ml)*	NA	105 ± 61.1	127 ± 89.0	136 ± 72.2	0.26
Total glutathione (μM)*	717–1110	852 ± 203	960 ± 148	922 ± 209	0.20
Oxidized glutathione (μM)*	1.17–5.32	1.01 ± 0.67	4.58 ± 11.0	4.93 ± 13.3	0.33
Glutathione peroxidase (UI/g Hb)*	20–58	51.5 ± 9.97	51.5 ± 11.5	51.0 ± 10.6	0.91
Myeloperoxidase (ng/ml)*	0–55	22.0 ± 24.4	53.4 ± 76.6	48.8 ± 95.9	0.28

*Log-transform applied to the variable.

**P-value from ordinal logistic regression.

NA = not available.