Table 4. Effect of galangin on reduced glutathione in the plasma and tissues of normal and STZ-induced diabetic rats.
Groups | Plasma GSH (mg/dl) | Tissue GSH (µg/mg protein) | |
---|---|---|---|
Liver | Kidney | ||
Control | 28.86 ± 1.78a | 14.25 ± 1.20a | 9.55 ± 0.74a |
Control + galangin (8 mg/kg BW) | 33.04 ± 2.85a | 14.92 ± 1.34a | 9.97 ± 1.62a |
Diabetic control | 16.65 ± 1.33b | 5.06 ± 0.36b | 4.82 ± 0.30b |
Diabetic + galangin (8 mg/kg BW) | 23.98 ± 1.56c | 12.08 ± 1.0c | 8.18 ± 0.60c |
Diabetic + glibenclamide (600 µg/kg BW) | 27.42 ± 2.64a,c | 13.64 ± 1.28a | 8.89 ± 0.57c |
Values are given as means ± S.D. from six rats in each group.
a,b,cValues not sharing a common superscript differ significantly at P < 0.05. DMRT.