Skip to main content
. 2013 Nov 15;18(4):155–164. doi: 10.1179/1351000213Y.0000000054

Table 2.

Effects of diazinon on testicle antioxidants and pro-oxidant (lipid peroxidation) level

Groups 1 week 2 weeks 8 weeks*
Reduced glutathione (μmol/g tissue)
Control 6.52 ± 0.02 6.49 ± 0.16 6.31 ± 0.08
10 mg/kg 6.00 ± 0.20 6.15 ± 0.06 5.08 ± 0.06**
15 mg/kg 5.80 ± 0.09** 5.75 ± 0.13** 5.37 ± 0.07**
30 mg/kg 5.71 ± 0.02** 5.62 ± 0.18** 4.18 ± 0.09**
Catalase (μmol H2O2 consumed/min/mg protein)
Control 0.21 ± 0.03 0.23 ± 0.03 0.57 ± 0.27
10 mg/kg 0.16 ± 0.02 0.21 ± 0.03 0.56 ± 0.03
15 mg/kg 0.13 ± 0.02 0.19 ± 0.03 0.48 ± 0.36
30 mg/kg 0.12 ± 0.03 0.17 ± 0.02 0.38 ± 0.03**
Lipid peroxidation (nmol MDA formed/g tissue)
Control 2.37 ± 0.19 2.17 ± 0.16 2.03 ± 0.04
10 mg/kg 2.88 ± 0.11 3.49 ± 0.16** 4.17 ± 0.08**
15 mg/kg 2.57 ± 0.16 4.12 ± 0.19** 4.83 ± 0.13**
30 mg/kg 3.15 ± 0.21 5.02 ± 0.19** 6.14 ± 0.04**

Results are expressed as mean ± SEM (n = 6).

* Significant (P < 0.05) increase or decrease of DZN time-dependent toxicity effect when compared to the one week exposure group.

** Significant (P < 0.05) increase or decrease of DZN dose-dependent toxicity effect when compared to the control.