Table 3.
Groups | Testosterone (ng/ml) | ||
---|---|---|---|
1 week | 2 weeks | 8 weeks | |
Control | 1.40 ± 0.02 | 1.65 ± 0.08 | 1.75 ± 0.04 |
10 mg/kg | 1.33 ± 0.02 | 1.60 ± 0.09 | 1.39 ± 0.03* |
15 mg/kg | 1.59 ± 0.04* | 1.54 ± 0.10 | 1.32 ± 0.04* |
30 mg/kg | 1.53 ± 0.03* | 1.15 ± 0.10* | 1.12 ± 0.03* |
Lactate dehydrogenase (mIU/ml) | |||
1 week | 2 weeks** | 8 weeks** | |
Control | 146.97 ± 11.05 | 147.82 ± 10.21 | 151.54 ± 9.56 |
10 mg/kg | 143.92 ± 11.94 | 209.63 ± 8.56* | 214.74 ± 10.08* |
15 mg/kg | 144.71 ± 12.26 | 219.76 ± 11.96* | 216.06 ± 12.68* |
30 mg/kg | 144.36 ± 8.32 | 232.85 ± 9.78* | 231.09 ± 12.73* |
Results are expressed as mean ± SEM (n = 6).
*Significant (P < 0.05) increase or decrease of DZN time-dependent toxicity effect when compared to the control.
**Significant (P < 0.05) increase or decrease of DZN dose-dependent toxicity effect when compared to the one week exposure group.