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. 2013 Nov 15;18(4):155–164. doi: 10.1179/1351000213Y.0000000054

Table 3.

The influence of diazinon on serum testosterone synthesis and lactate dehydrogenase activity

Groups Testosterone (ng/ml)
1 week 2 weeks 8 weeks
Control 1.40 ± 0.02 1.65 ± 0.08 1.75 ± 0.04
10 mg/kg 1.33 ± 0.02 1.60 ± 0.09 1.39 ± 0.03*
15 mg/kg 1.59 ± 0.04* 1.54 ± 0.10 1.32 ± 0.04*
30 mg/kg 1.53 ± 0.03* 1.15 ± 0.10* 1.12 ± 0.03*
  Lactate dehydrogenase (mIU/ml)
  1 week 2 weeks** 8 weeks**
Control 146.97 ± 11.05 147.82 ± 10.21 151.54 ± 9.56
10 mg/kg 143.92 ± 11.94 209.63 ± 8.56* 214.74 ± 10.08*
15 mg/kg 144.71 ± 12.26 219.76 ± 11.96* 216.06 ± 12.68*
30 mg/kg 144.36 ± 8.32 232.85 ± 9.78* 231.09 ± 12.73*

Results are expressed as mean ± SEM (n = 6).

*Significant (P < 0.05) increase or decrease of DZN time-dependent toxicity effect when compared to the control.

**Significant (P < 0.05) increase or decrease of DZN dose-dependent toxicity effect when compared to the one week exposure group.