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. 2013 Nov 15;18(4):155–164. doi: 10.1179/1351000213Y.0000000054

Table 4.

Diazinon induced gonadotoxicity effects

Groups 1 week 2 weeks 8 weeks*
Concentration (millions/ml)
Control 72.50 ± 2.14 67.50 ± 4.74 69.83 ± 4.23
10 mg/kg 68.00 ± 5.20 69.33 ± 4.56 95.67 ± 4.57
15 mg/kg 72.50 ± 5.86 57.67 ± 5.12 72.83 ± 5.59
30 mg/kg 64.50 ± 4.75 74.83 ± 4.78 87.00 ± 4.78
Abnormality (%)
Control 18.67 ± 0.94 14.75 ± 1.12 19.67 ± 0.56
10 mg/kg 22.08 ± 1.32 12.08 ± 1.11 24.17 ± 0.84**
15 mg/kg 16.75 ± 1.22 13.83 ± 1.17 28.33 ± 0.82**
30 mg/kg 21.67 ± 1.46 13.50 ± 1.37 29.83 ± 0.86**
Seminiferous tubular diameter (μm)
Control 520.51 ± 9.58 512.78 ± 12.33 548.95 ± 21.74
10 mg/kg 517.64 ± 12.31 539.53 ± 16.52 538.64 ± 13.94
15 mg/kg 513.92 ± 11.68 524.67 ± 15.23 533.90 ± 22.37
30 mg/kg 486.12 ± 8.23 502.46 ± 22.67 578.72 ± 20.89

Results are expressed as mean ± SEM (n = 6).

*Significant (P < 0.05) increase or decrease of DZN time-dependent toxicity effect when compared to the one week exposure group.

** Significant (P < 0.05) increase or decrease of DZN dose-dependent toxicity effect when compared to the control.