Table 4.
Groups | 1 week | 2 weeks | 8 weeks* |
---|---|---|---|
Concentration (millions/ml) | |||
Control | 72.50 ± 2.14 | 67.50 ± 4.74 | 69.83 ± 4.23 |
10 mg/kg | 68.00 ± 5.20 | 69.33 ± 4.56 | 95.67 ± 4.57 |
15 mg/kg | 72.50 ± 5.86 | 57.67 ± 5.12 | 72.83 ± 5.59 |
30 mg/kg | 64.50 ± 4.75 | 74.83 ± 4.78 | 87.00 ± 4.78 |
Abnormality (%) | |||
Control | 18.67 ± 0.94 | 14.75 ± 1.12 | 19.67 ± 0.56 |
10 mg/kg | 22.08 ± 1.32 | 12.08 ± 1.11 | 24.17 ± 0.84** |
15 mg/kg | 16.75 ± 1.22 | 13.83 ± 1.17 | 28.33 ± 0.82** |
30 mg/kg | 21.67 ± 1.46 | 13.50 ± 1.37 | 29.83 ± 0.86** |
Seminiferous tubular diameter (μm) | |||
Control | 520.51 ± 9.58 | 512.78 ± 12.33 | 548.95 ± 21.74 |
10 mg/kg | 517.64 ± 12.31 | 539.53 ± 16.52 | 538.64 ± 13.94 |
15 mg/kg | 513.92 ± 11.68 | 524.67 ± 15.23 | 533.90 ± 22.37 |
30 mg/kg | 486.12 ± 8.23 | 502.46 ± 22.67 | 578.72 ± 20.89 |
Results are expressed as mean ± SEM (n = 6).
*Significant (P < 0.05) increase or decrease of DZN time-dependent toxicity effect when compared to the one week exposure group.
** Significant (P < 0.05) increase or decrease of DZN dose-dependent toxicity effect when compared to the control.