Table 1. Patient and sample information.
| Case ID | PID | Age at initial sampling (years) | Specimen type | Wks after initial sample | RV RNA amount a | Virus isolation | Isolate name | Designation for genome sequence |
|---|---|---|---|---|---|---|---|---|
| CA | AT | 10 | skin biopsy | 0 | 1.8x104 | Pos | CA6944 | RVi/California.USA/43.16/GR RVs/California.USA/43.16/GR |
| buccal swab | 0 | 0 | n.t. | |||||
| buccal swab | 0 | 0 | n.t. | |||||
| throat swab | 8 | 0 | n.t. | |||||
| urine | 8 | 0 | n.t. | |||||
| serum | 8 | 0 | n.t. | |||||
| swab lesion 1 | 8 | 0 | n.t. | |||||
| swab lesion 2 | 8 | 0 | n.t. | |||||
| RI | AT | 17 | skin biopsy | 0 | 1.7x105 | Pos | RI6318 | RVi/RhodeIsland.USA/9.17/GR RVs/RhodeIsland.USA/9.17/GR |
| NP swab | 0 | 0 | n.t. | |||||
| urine | 0 | 0 | n.t. | |||||
| PBMC | 0 | 0 | Neg | |||||
| serum | 14 | 0 | n.t. | |||||
| LA | AT | 6 | skin biopsy | 0 | 5.6x103 | Pos | LA3331 | RVi/Louisiana.USA/27.17/GR RVs/Louisiana.USA/27.17/GR |
| throat swab | 3 | 0 | n.t. | |||||
| urine | 6 | 0 | n.t. | |||||
| serum | 6 | 0 | n.t. | |||||
| NP swab | 0 | 2.0x102 | Neg | RVs/Louisiana.USA/27.17/NP | ||||
| NP swab | 3 | 3.7x102 | Neg | |||||
| NP swab | 9 | 0 | n.t. | |||||
| NP swab | 12 | 0 | n.t. | |||||
| NP swab | 15 | 0 | n.t. | |||||
| OR | NBS | 11 | NP swab | 0 | 0 | n.t. | ||
| skin biopsy | 6 | 1.2x104 | Pos | OR5810 | RVi/Oregon.USA/05.18/GR RVs/Oregon.USA/05.18/GR |
a—expressed as total RNA copies/entire skin biopsy or RNA copies/ml of NP swab sample
Abbreviations: AT—ataxia telangiectasia; NBS- Nijmegen breakage syndrome; NP–nasopharyngeal; n.t.—not tested (virus culture was not performed for RT-PCR negative samples).