(A) Renal cortex of a control rat showing normal architecture (H&E, ×100). (B) Renal medulla of a control rat showing normal architecture (H&E, ×100). (C) Renal cortex of an AG-treated rat showing normal architecture (H&E, ×100). (D) Renal medulla of an AG-treated rat showing normal morphology (H&E, ×100). (E) Renal cortex of a CP-treated rat. Diffuse glomerular and tubular nephritis was observed (H&E, ×100). (F) Renal medulla of CP-treated rat. Tubules in the medulla were enlarged with edema (arrow) with hypertrophied lining epithelial cells (H&E, ×100). (G) Kidney cortex of AG + CP-treated rat. The cortex showed almost normal architecture (H&E, ×100). (H) Kidney medulla of AG + CP-treated rat. The medulla showed normal architecture (H&E, ×100).