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. 2013 Jul 19;17(4):145–156. doi: 10.1179/1351000212Y.0000000017

Table 4.

Cytotoxic effects of the extracts of A. aspera on four different cancer cell lines and a normal cell line at various time intervals

	IC₅₀ (μg/ml)
	VERO	AGS	MCF-7	A 549	COLO 320 DM
A. aspera
24 hours
Hexane	221 ± 16^b	142 ± 10^d	98 ± 7^e	182 ± 13^c	241 ± 18^a
Ethyl acetate	741 ± 56^a	346 ± 26^d	421 ± 32^c	515 ± 39^b	441 ± 33^c
Methanol	682 ± 51^a	224 ± 17^c	315 ± 24^b	285 ± 21^b	321 ± 24^b
48 hours
Hexane	185 ± 14^b	115 ± 8^d	82 ± 6^e	152 ± 11^c	212 ± 16^a
Ethyl acetate	687 ± 52^a	291 ± 22^e	342 ± 26^d	468 ± 35^b	386 ± 29^c
Methanol	412 ± 31^a	196 ± 14^c	286 ± 21^b	206 ± 15^c	294 ± 22^b
72 hours
Hexane	156 ± 11^b	84 ± 6^d	63 ± 4^e	131 ± 10^c	189 ± 14^a
Ethyl acetate	212 ± 16^d	246 ± 18^c	254 ± 19^b	183 ± 14 ^e	266 ± 20 ^a
Methanol	394 ± 30^a	152 ± 11^c	192 ± 14^d	143 ± 10 ^c	235 ± 17 ^b

Each value represents the mean ± SD for six replicates in each group.

Different letters in a row indicate P < 0.05 by DMRT.