Table 1. Acute antihyperglycemic effect of FIIc at various time intervals in diabetic rats.

Groups	Dose (per kg bwt.)	Blood glucose (mg/dl)
		Fasting			After treatment
		0 hour	90 minutes	%Fall	3 hours	%Fall	5 hours	%Fall
Control animals	Vehicle	79 ± 3.2	82 ± 2.9	–	80.5 ± 3.4	–	79.2 ± 2.8	–
Diabetic animals	Vehicle	303 ± 8.2	302 ± 6.9	–	306 ± 3.4	–	308 ± 7.1	–
Diabetic + gliben	600 µg	300 ± 7.2	278 ± 4.9a	7.2	269.5 ± 5.2a	10.2	258.5 ± 4.8a	13.8
Diabetic + FIIc	10 mg	305 ± 6.9	292 ± 3.1	4	275 ± 6.2	9.8	265 ± 4.5a	13.1
Diabetic + FIIc	15 mg	304 ± 7.1	283 ± 4.2	6.9	249 ± 3.9a	18.1	239.5 ± 3.1a	21.2
Diabetic + FIIc	20 mg	303 ± 6.6	281.3 ± 3.7a	7.16	246.5 ± 3.6a	18.6	238 ± 2.9a	21.4

Notes: Values are mean  ±  SEM for five animals in each group. FIIc: purified active compound; gliben: glibenclamide. %Fall was calculated as the difference between the two values/starting value × 100.

^aP < 0.001 vs. compared to 0 hour.