Table 3. Effect of FIIc (15 mg/kg bwt.) on key hepatic carbohydrate-related enzyme activity in diabetic rats after 8 weeks treatment.
Groups | Hexokinase (U/mg of protein) | Phosphofructokinase (U/mg of protein) | Fructose-1,6-bisphosphatase (U/g of protein) | Glucose-6-pase (U/mg of protein) |
---|---|---|---|---|
Control animals | 0.219 ± .021 | 12.85 ± 0.35 | 58.01 ± 3.2 | 17.36 ± 0.48 |
Diabetic animals | 0.082 ± 0.007a | 4.19 ± 0.31a | 195.8 ± 6.5a | 45.17 ± 1.32a |
Diabetic + FIIc | 0.192 ± 0.012b | 11.21 ± 0.24b | 75.6 ± 4.9b | 19.82 ± 0.99b |
Diabetic + glibe. | 0.189 ± 0.016b | 10.49 ± 0.20b | 99.8 ± 05.2b | 23.31 ± 1.12b |
Note: Values are mean ± SEM for five animals in each group.
aP < 0.001 vs. healthy control.
bP < 0.001 vs. diabetic control.