Table 5. Effect of FIIc (15 mg/kg bwt.) on oxidative stress parameters in diabetic rats after 8 weeks of treatment.
Groups | Serum MDA (nmol/L) | GSH (mg/g of Hb) | SOD (U/g of Hb) | Catalase (U/g of Hb) |
---|---|---|---|---|
Control animals | 2.06 ± 0.11 | 2.89 ± 0.05 | 1980.20 ± 96 | 3.39 ± 0.06 |
Diabetic animals | 4.21 ± 0.14a | 1.89 ± 0.15a | 1040.60 ± 127a | 1.63 ± 0.30a |
Diabetic + FIIc | 2.23 ± 0.21b | 2.65 ± 0.16b | 1841.60 ± 129b | 3.25 ± 0.11b |
Diabetic + glibe | 2.75 ± 0.25b | 2.56 ± 0.12b | 1842.60 ± 53b | 3.06 ± 0.18b |
Note: Values are mean ± SEM for five animals in each group.
aP < 0.001 vs. healthy control.
bP < 0.001 vs. diabetic control.