Table 2. Oxidative stress markers at 4 months by treatment group (mean values and mean differences adjusted for baseline values).
Outcome | Control (n = 17) | Pentoxifylline (n = 15) | Difference (pentoxifylline-control) (95% CI) | P-value |
---|---|---|---|---|
Total F2-isoprostanes (pg/ml) | 134.32 (105.20–163.44) | 169.33 (138.28–200.38) | 35.01 (−8.12 to 78.15) | 0.11 |
Plasma GPX (U/l) | 178.81 (174.09–183.54) | 172.75 (167.71–177.78) | −6.06 (−13.0 to 0.89) | 0.09 |
Plasma SOD (U/ml) | 2.17 (1.56–2.78) | 2.99 (2.33–3.64) | 0.82 (−0.08 to 1.71) | 0.07 |
Protein carbonyls (nmol/mg) | 0.63 (0.55–0.71) | 0.59 (0.50–0.68) | −0.04 (−0.16 to 0.08) | 0.52 |