Skip to main content
. Author manuscript; available in PMC: 2020 Feb 12.
Published in final edited form as: Nat Phys. 2019 Aug 12;15(11):1195–1203. doi: 10.1038/s41567-019-0618-1

Figure 2. A vertex model of wound healing predicts that intercalation is necessary for wound closure and cell shape maintenance.

Figure 2

a-f, Vertex model simulations. a, b, Percentage of initial wound area and wound junctions after ablation with intercalations (a) disabled, and (b) enabled. c, d,Vertex model simulation images after ablation with intercalations (c) disabled, and (d) enabled. e, f, Percentage change in cell elongation over time during and after wound closure, calculated by dividing the major axis by the minor axis of an ellipse fit to each cell, for the first three rows of cells around the wound with intercalations (e) disabled, and (f) enabled.