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. Author manuscript; available in PMC: 2020 Apr 23.
Published in final edited form as: Nature. 2019 Oct 23;574(7779):549–552. doi: 10.1038/s41586-019-1662-9

Extended Data Figure 6. Starting phage titre does not affect CRISPR evolution in the presence of a microbial community.

Extended Data Figure 6

Proportion of P. aeruginosa that acquired CRISPR-based resistance at 3 days post infection with varying starting titres of phage DMS3vir when grown in polyculture (n = 127 biologically independent samples). Deviance test: Start phage and CRISPR; Residual deviance(20, n = 24) = 2.00, p = 0.13; Tukey contrasts: 102 v 104; z = -1.52, p = 0.42; 104 v 106; z = -0.76, p = 0.87; 106 v 108; z = 1.31, p = 0.56; 102 v 106; z = -2.24, p = 0.11; 102 v 108; z = -0.99, p = 0.75; 104 v 108; z = 0.56, p = 0.94. Error bars correspond to ± one standard error, with the mean as the measure of centre.