Study design of the OPTIMAL study. Bx, baseline; CAD, coronary artery disease; CGM, continuous glucose monitoring; CV, coefficient of variance; HbA1c, glycated hemoglobin; IVUS, intravascular ultrasound; mo, month; NIRS, near-infrared spectroscopy; PCI, percutaneous coronary intervention; SU, sulphonylurea; T2DM, type 2 diabetes mellitus.