Table 3. Stratified analysis of the diagnostic performance of 50% diameter stenosis by 2-dimensional and 3-dimensional quantitative coronary angiography for predicting fractional flow reserve ≤0.80 according to different lesion locations.
| Index | LAD | LCx | RCA | P value |
|---|---|---|---|---|
| 2D-QCA 50% DS | ||||
| Accuracy | 61.8 (56.7–66.9) | 66.4 (58.2–74.6) | 70.8 (63.7–77.9) | 0.13 |
| Sensitivity | 39.6 (32.0–47.7) | 75.0 (55.1–89.3) | 58.3 (40.8–74.5) | <0.001 |
| Specificity | 79.9 (73.6–85.3) | 64.1 (54.0–73.3) | 74.7 (65.8–81.8) | 0.01 |
| 3D-QCA 50% DS | ||||
| Accuracy | 74.5 (70.0–79.1) | 69.4 (61.5–77.5) | 76.4 (69.8–83.0) | 0.38 |
| Sensitivity | 61.6 (53.6–69.2) | 85.7 (67.3–96.0) | 88.9 (73.9–96.9) | 0.004 |
| Specificity | 85.1 (79.2–89.8) | 65.0 (55.0–74.2) | 72.8 (64.1–80.4) | <0.001 |
Values are n% (95% CI). Comparisons for accuracy, sensitivity and specificity among lesion groups of LAD, LCx and RCA were performed by chi-squared test. 2D-QCA, 2-dimensional quantitative coronary angiography; 3D-QCA, 3-dimensional quantitative coronary angiography; DS%, percent diameter stenosis; LAD, left anterior descending artery; LCx, left circumflex; RCA, right coronary artery.