Proportion of patients with pathogenic variants (class 5, red bars), probably pathogenic variants (class 4, orange bars) and variants of uncertain significance (class 3, grey bars). Cohorts: LQTS =649, BrS =152, CPVT =88, ARVC =126, HCM =242, DCM =128. See online: http://fp.amegroups.cn/cms/0333ca39cab639893ad880e964e959c5/cdt.2019.06.06-1.pdf. LQTS, long QT syndrome; BrS, Brugada syndrome; CPVT, catecholaminergic polymorphic ventricular tachycardia; ARVC, arrhythmogenic right ventricular cardiomyopathy; HCM, hypertrophic cardiomyopathy; DCM, dilatative cardiomyopathy.