Table 3. Global assessment of hepatic alterations.
Patient | Type of surgery | Functional class (NYHA) | Body mass index (kg/m2 body surface area) | Ejection fraction of sub-pulmonary ventricle (%) | Qualitative system-ventricle function (RV) | Abdominal sonography (normal/abnormal) | Staging of fibrosis | Pathological laboratory findings | AST/ALT-ratio | Fibrosis scores | Global hepatic assessment | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient elastography | ARFI | NAFLD | BARD | FORNS | Hepatic alteration | Kind of damage | ||||||||||
BE | Senning | 2 | 17.5 | 80 | Mildly depressed | Normal | 1 | 2 | Total bilirubin | 1.3* | −3.038 | 2* | 3.45 | Yes | Fibrosis | |
DM | Senning | 2 | 18.4 | 88 | Mildly depressed | Abnormal | 4 | 2 | GGT | 1.4* | −2.635 | 2* | 4.77 | Yes | Fibrosis | |
BF | Mustard | 1 | 24.4 | 65 | Mildly depressed | Normal | 1 | 1 | – | 0.8 | −3.296 | 2* | 3.85 | No | – | |
DR | Senning | 1 | 22.5 | 74 | Mildly depressed | Abnormal | 3 | 2 | – | 0.8 | −3.461 | 2* | 3.54 | Yes | Fibrosis | |
FCM | Mustard | 1 | 29.4 | 78 | Normal | Normal | 1 | 1 | – | 0.8 | −2.259 | 3* | 4.09 | No | – | |
PS | Mustard | 1 | 23.9 | 71 | Mildly depressed | Normal | 1 | 0 | – | 1.1* | −3.546 | 2* | 3.28 | No | – | |
KJW | Subject | 2 | 26.8 | 72 | Mildly depressed | Normal | NA | 0 | Total bilirubin | 0.9 | −3.348 | 3* | 1.90 | No | – | |
FB | Mustard | 2 | 21.1 | 76 | Normal | Normal | 1 | 2 | – | 1.3* | −2.614 | 2* | 3.55 | Yes | Fibrosis | |
JS | Mustard | 2 | 27.8 | 65 | Mildly depressed | Abnormal | 4 | 4 | GGT | 0.7 | −2.879 | 0 | 5.39 | Yes | Cirrhosis | |
MW | Mustard | 1 | 23.7 | 80 | Normal | Normal | 3 | 1 | GGT | 1.3* | −3.325 | 2* | 4.14 | Yes | Fibrosis | |
SP | Senning | 2 | 24.3 | 77 | Mildly depressed | Normal | 2 | 3 | – | 0.8 | −3.550 | 2* | 3.03 | Yes | Fibrosis | |
IH | Senning | 1 | 27.5 | 84 | Mildly depressed | Normal | 1 | 1 | – | 0.9 | −3.259 | 2* | 2.07 | No | – | |
MZ | Senning | 1 | 24.2 | 86 | Mildly depressed | Normal | 2 | 3 | GGT | 0.8 | −3.324 | 2* | 3.41 | Yes | Fibrosis | |
MW | Mustard | 2 | 25.8 | 64 | Mildly depressed | Abnormal | NA | 3 | GGT | 0.8 | −2.175 | 2* | 5.49 | Yes | Fibrosis | |
AR | Senning | 2 | 37.5 | 68 | Mildly depressed | Normal | NA | 0 | GGT | 0.6 | −1.426 | 1 | 3.28 | No | – | |
MF | Senning | 1 | 19.4 | NA | Normal | Normal | 1 | 4 | – | 1.2* | −4.767 | 2* | 0.99 | Yes | Cirrhosis | |
RL | Senning | 1 | 28.1 | NA | Normal | Abnormal | 4 | 3 | GGT, ALT | 0.6 | −3.019 | 1 | 4.45 | Yes | Cirrhosis | |
WK | Senning | 3 | 22.4 | NA | Normal | Abnormal | 3 | 4 | GGT | 0.9 | −2.906 | 2* | 5.19 | Yes | Cirrhosis | |
SH | Mustard | 1 | 26.1 | 82 | Normal | Abnormal | n.a | 4 | Total bilirubin, GGT, AP | 0.9 | −1.699 | 2* | 6.84 | Yes | Cirrhosis | |
SF | Senning | 1 | 32.1 | NA | NA | NA | 2 | NA | Total bilirubin, AST, ALT | 0.4 | −3.180 | 1 | 2.71 | Yes | Fibrosis | |
DK | Mustard | 1 | 20.5 | 54 | NA | NA | 1 | NA | – | 0.8 | −3.763 | 2* | 3.17 | No | – | |
TB | Mustard | 1 | 22.1 | 57 | NA | NA | 2 | NA | – | 0.9 | −3.386 | 2* | 2.07 | Yes | Fibrosis | |
JSS | Mustard | 1 | 23.9 | 74 | NA | NA | 2 | NA | Total bilirubin | 0.6 | −3.834 | 0 | 2.61 | Yes | Fibrosis | |
KHN | Senning | 3 | 23.5 | NA | Mildly depressed | Normal | 4 | 3 | GGT | 0.4 | −4.611 | 0 | 2.79 | Yes | Cirrhosis |
*, values suspicious for relevant liver fibrosis. ARFI, acoustic radiation force impulse; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transpeptidase; NA, not available.