Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 1;7:253. doi: 10.3389/fcell.2019.00253

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Han, Liu, Zhen, Yuan, Zhang, Song, Dong, Yao and Qu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

STAT3 and miR-384 mediate Th17 polarization. CD4⁺ naïve T cells are cultured in Th17 polarizing conditions with AG490 or miR-384 inhibitor (miR-384 I) for 3 days, and then miR-384 transcription is measured by qRT-PCR (A), percentage of stimulated IL-17⁺ cells is tested by flow cytometry (B,C), dose of IL-17 in culture supernatant is measured by ELISA (D), and Rorγt mRNA (E) and SOCS3 mRNA (F) levels are analyzed by qRT-PCR. Data are presented as mean ± standard deviation. ^∗P < 0.05. ^∗∗P < 0.01. ^∗∗∗P < 0.001. Data are representative of three experiments done in triplicate.