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. 2019 Nov 1;10:803. doi: 10.3389/fpsyt.2019.00803

Table 4.

Body fat composition before and after re-installing SGAs in patients with schizophrenia during a 6-week treatment with olanzapine depending on the presence or absence of MetS [Me (Q1; Q3)].

Time-point for the assessment Patients with MetS (n = 10) p-value Patients without MetS (n = 20) p-value
Total body fat percentage
At hospitalization 46.5 [36; 53.6] 0.944 31.2 [22.6; 30.0] 0.005*
After a 6-week treatment 45.5 [35.9; 53.7] 35.1 [25.4; 44.1]
Visceral fat level
At hospitalization 13 [9; 18] 0.963 7 [4; 8] 0.034*
After a 6-week treatment 13 [10; 17] 8 [5; 9]
Total fat fold
At hospitalization, mm 119 [102; 146] 0.341 84 [68; 116] <0.001*
After a 6-week treatment, mm 124 [104; 146] 85 [70; 118]
Waist circumference
At hospitalization, cm 114 [103; 125] 0.105 87 [80; 95] 0.020*
After a 6-week treatment, cm 115 [105; 125] 88 [80; 95]
Body weight
At hospitalization, kg 103.1 [95.0; 119.1] 0.306 73.7 [62.3; 87.9] 0.029*
After a 6-week treatment, kg 103.3 [96.4; 117.6] 74.2 [64; 89.5]
Body mass index
At hospitalization 36.1 [34.5; 37.8] 0.889 25.0 [22.6; 30.0] 0.023*
After a 6-week treatment 36.0 [34.4; 37.8] 26.7 [23.6; 34.1]

*p < 0.05—statistically significant difference. Comparisons between groups were performed using the Wilcoxon signed-rank test.