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. 2019 Nov 1;10:2509. doi: 10.3389/fmicb.2019.02509

FIGURE 3.

FIGURE 3

Virulence of OXA-48 producing Enterobacteriaceae clinical isolates in the Galleria mellonella in vivo infection model. (A) Dose-dependent mortality of G. mellonella infected with KP980. Different cfu were injected into the larvae and survival was monitored for 72 h. Error bars show standard error of the mean. (B) Log median lethal dose (LD50) of clinical E. coli isolates. (C) LD50 of K. pneumoniae isolates. Mean values from three to four independent experiments with 12 larvae in each group are shown. Error bars represent the 95% confidence interval. ∗∗∗P < 0.0001; ∗P < 0.05 (Mann–Whitney U test).