TABLE 2.
Isolate |
Genetic support of OXA-48 |
MIC (mg/L) |
|||||||||
Isolatea | ST (Pasteur) | Specimen | Transposon | Plasmid size | IncL | CTX | CAZ | ETP | IMP | MEM | CIP |
KP659 | 15 | Stool | Tn1999.2 | 63 kb | + | >256 | 32 | >32 | 0.5 | 2 | >32 |
KP920 | 16 | Wound swab | Tn1999.2 | 63 kb | + | >256 | >256 | >32 | >32 | >32 | >32 |
KP980 | 16 | Rectal swab | Tn1999.2 | 63 kb | + | >256H | 16 | >32 | 2 | 2 | >32 |
KP1151 | 15 | Rectal swab | Tn1999.2 | 63 kb | + | >256 | >256 | >32 | >32 | >32 | >32 |
KP1664 | 16 | Throat swab | Tn1999.2 | 63 kb | + | 256H | 64 | 32 | 32 | 32 | >32 |
KP1673 | 101 | Urine | Tn1999.2 | 63 kb | + | >256 | >256 | >32 | 32 | >32 | >32 |
KP1696 | 377 | Skin swab | invTn1999.2 | 63 kb | + | >256 | >256 | 3 | 1 | 1 | >32 |
KP1766 | 1658 | Skin swab | invTn1999.2 | 63 kb | + | >256 | >256 | >32 | 16 | 32 | >32 |
KP1982 | 377 | Wound swab | Tn1999.2 | 63 kb | + | >256 | >256 | 32 | 8 | 16 | >32 |
KP2255 | 437 | Rectal swab | invTn1999.2 | 63 kb | + | >256 | 128 | 32 | 32 | 32 | >32 |
KP2451 | 392 | Rectal swab | Tn1999.2 | 63 kb | + | >256 | >256 | 2 | 16 | 4 | >32 |
KP2540 | 392 | Rectal swab | invTn1999.2 | 63 kb | + | 64 | 128 | 2 | 4 | 2 | > 32 |
KP2575 | 3384 | Rectal swab | Tn1999 | 63 kb | + | 4 | 2 | >32 | 8 | 8 | 0.06 |
KP2670 | 101 | Tracheal secretion | Tn1999 | 63 kb | + | 0.5 | 0.25 | 2 | 2 | 1 | 0.03 |
KP2746 | 101 | Liver biopsy | invTn1999.2 | 63 kb | + | 2 | 0.5 | 16 | 8 | 4 | 0.03 |
KP3379 | 307 | Urine | Tn1999.2 | 63 kb | + | 2 | 1 | 4 | 2 | 4 | 16 |
KP3907 | 307 | Stool | Tn1999.2 | 63 kb | + | >256 | 32 | >32 | 2 | 1 | >32 |
KP12536 | 3385 | Tracheal secretion | Tn1999.2 | 63 kb | + | 0.5 | 0.25 | 16 | 2 | 4 | 0.03 |
KP12883 | 323 | Urine | invTn1999.2 | 63 kb | + | 0.5 | 0.25 | 1 | 8 | 1 | >32 |
KP13815 | 11 | Wound swab | Tn1999.2 | 63 kb | + | >256 | >256 | 2 | 4 | 2 | >32 |
H, heteroresistance; CTX, cefotaxime; CAZ, ceftazidime; ETP, ertapenem; IMP, imipenem; MEM, meropenem; CIP, ciprofloxacin; aIsolates which were further assessed in virulence assays are highlighted in bold.