Table 1.
Enriched pathways in the HSG group.
| Description | Observed | Background | FDR | Matching protein from the data set |
|---|---|---|---|---|
|
Oxidative phosphorylation (oas00190) |
25 | 119 | 3.05e-19 | ATP5D,ATP5I,ATP6,COX1,COX2,COX4I1,CYC1,CYTB,ENSOARG00000004138,ND4,ND5,ND6,NDUFA11,NDUFA13,NDUFA3,NDUFA7,NDUFA8,NDUFB2,NDUFB7,NDUFS7,NDUFS8,NDUFV1,SDHA,UQCR10,UQCRC1 |
|
Thermogenesis (oas04714) |
27 | 211 | 2.17e-16 | ATP5D,ATP5I,ATP6,COX1,COX2,COX4I1,CYC1,CYTB,ENSOARG00000004138,MAPK13,ND4,ND5,ND6,NDUFA11,NDUFA13,NDUFA3,NDUFA7,NDUFA8,NDUFB2,NDUFB7,NDUFS7,NDUFS8,NDUFV1,RPS6KA1,SDHA,UQCR10,UQCRC1 |
|
Metabolic pathways (oas01100) |
49 | 1215 | 3.49e-11 | ACSS1,ALDOA,ALPL,APRT,ATP5D,ATP5I,ATP6,B4GALT2,BCAT2,COX1,COX2,COX4I1,CYC1,CYTB,DGKZ,DPM3,ENO1,ENSOARG00000004138,G6PC3,GALK1,GAPDH,HK1,HK3,NADSYN1,ND4,ND5,ND6,NDUFA11,NDUFA13,NDUFA3,NDUFA7,NDUFA8,NDUFB2,NDUFB7,NDUFS7,NDUFS8,NDUFV1,PAFAH1B3,PFKL,PGLS,PGM1,PKM,RRM2B,SDHA,TK1,TPI1,TSTA3,UQCR10,UQCRC1 |
|
Retrograde endocannabinoid signaling (oas04723) |
16 | 129 | 1.08e-09 | DAGLB,GNB2,MAPK13,ND4,ND5,ND6,NDUFA11,NDUFA13,NDUFA3,NDUFA7,NDUFA8,NDUFB2,NDUFB7,NDUFS7,NDUFS8,NDUFV1 |
|
Glycolysis/Gluconeogenesis (oas00010) |
11 | 62 | 3.92e-08 | ACSS1,ALDOA,ENO1,G6PC3,GAPDH,HK1,HK3,PFKL,PGM1,PKM,TPI1 |
|
Ribosome (oas03010) |
14 | 160 | 8.85e-07 | ENSOARG00000005542,ENSOARG00000010831,ENSOARG00000011932,ENSOARG00000017508,ENSOARG00000019510,ENSOARG00000020159,MRPL28,MRPL34,RPL13A,RPL18A,RPL28,RPL8,RPS21,RPS9 |
|
Galactose metabolism (oas00052) |
7 | 30 | 5.72e-06 | B4GALT2,G6PC3,GALK1,HK1,HK3,PFKL,PGM1 |
|
Carbon metabolism (oas01200) |
11 | 108 | 5.72e-06 | ACSS1,ALDOA,ENO1,GAPDH,HK1,HK3,PFKL,PGLS,PKM,SDHA,TPI1 |
| Fructose and mannose metabolism (oas00051) | 6 | 31 | 8.95e-05 | ALDOA,HK1,HK3,PFKL,TPI1,TSTA3 |
The most enriched pathways using the up-regulated genes following 30-days hemp seed dietary supplementation.