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. 2019 Nov 7;9:16259. doi: 10.1038/s41598-019-52770-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Up-regulation of miR-146a and down-regulation of TRAF6 mRNA in CF macrophages. (a) MiR-146a levels were measured using RT-qPCR in non-CF (n = 16) and CF (n = 11) macrophages. The data were normalised to expression of the RNU6B endogenous control. Each symbol represents a single individual. **p < 0.01 (Mann-Whitney tests) (b,c) TRAF6 and IRAK1 mRNAs were evaluated using RT-qPCR in non-CF (n = 8) and CF (n = 8) macrophages. The data were normalised to expression of the endogenous β-actin control. Data are means ± SEM. *p < 0.05 (unpaired t-tests).