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. 2019 Nov 7;9:16232. doi: 10.1038/s41598-019-52810-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Treatment condition differences in cortisol. Plasma levels of cortisol measured in drug-free conditions before (baseline) and after the first and last novel environment test sessions are presented as mean ± SEM. Treatment conditions are ordered in terms of increasing exposure to more stress elements as described in Table 1. Asterisks indicate a significant difference relative to the No SI condition (P < 0.05).