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. 2019 Nov 7;10:5068. doi: 10.1038/s41467-019-12927-7

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Models for the emergence of the founder isolate of the Pgt Ug99 lineage. a A somatic hybridisation event and nuclear exchange occurred between an isolate of the Pgt 21 lineage and an unknown Pgt isolate. The combination of nuclei A and C yielded the parental isolate of the Ug99 lineage in Africa. Under this scenario, nucleus A of Ug99 is entirely derived from nucleus A in Pgt21-0. b Alternatively, sexual reproduction and mating between these two parental isolates defined the origin of the Ug99 lineage. Under this scenario, meiotic recombination and chromosome reassortment would result in the Pgt21-0-derived A nucleus of Ug99 being composed of a mosaic of the two haploid nuclear genomes of Pgt21-0 (X and Y)