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. 2019 Nov 1;7:294. doi: 10.3389/fbioe.2019.00294

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Copyright © 2019 Mendes-Pinheiro, Anjo, Manadas, Da Silva, Marote, Behie, Teixeira and Salgado.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene ontology analyses of the identified proteins in a proteomic analysis of the hBMSCs secretome from three independent donors. Categorization of the most represented (A) molecular functions, (B) protein classes, and (C) signaling pathways, using the PANTHER software (gene ontology levels 2 and 3). Results are shown as the percentage of proteins that are part of each individual GO category. Categorization of the enrichment of (D) cellular components, (E) elements of the proteasome and (F) elements of histones, using the ConsensusPathDB software (gene ontology levels 4 and 5). Results are shown as the –log of the p-value for the enrichment of each individual category.