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. 2019 Nov 1;10:2558. doi: 10.3389/fimmu.2019.02558

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Copyright © 2019 Enos, Takenaka, Scott, Salfity, Kirk, Egar, Sarria, Slayback-Barry, Belecky-Adams and Chernoff.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD36 inhibition reduces DiI-Ox-LDL uptake by foamy macrophages. Seventeen days regenerate spinal cord regenerate explants, were treated with DiI-Ox-LDL at 10DIV for 24 h as the control (A) or with the CD36 inhibitor sulfo-N-succinimidyl oleate added at 10DIV plus DiI-Ox-LDL added at 11DIV for 24 h. (B) Inhibitor-treated explants showed less uptake of DiI-Ox-LDL in comparison to control. D, day; DIV, days in vitro; Ox-LDL, oxidized low-density receptor; inhib, inhibitor; Regen, regeneration. Magnification bar is shown in the lower portion of each image.