Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 7;9:16278. doi: 10.1038/s41598-019-52637-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Change in the hydration pattern upon U to Ψ modification for duplex-CΨG and duplex-CUG. RDFs of water oxygen atoms (a) around the HN1-Ψ5 and H5-U5 atoms, respectively; (b) around the geometric center of the OP2-Ψ5 and HN1-Ψ5 atoms or OP2-U5 and H5-U5 atoms. Red – Ψ-modified duplexes; Black – unmodified duplexes. Water occupancy contoured at equivalent levels and hydrogen bonding patterns (in dotted lines) viewed from the major groove. (c) Reference duplex-CUG; (d) Ψ-modified duplex-CΨG; differences in hydration patterns are shown in solid. (e) Snapshot of two water molecules making contact between HN1, OP2 atoms of Ψ and OP2 atom of the preceding residue.