Fig. 5.

a SEM images displaying a cross-section of a tri-layered tubular graft. b The aligned structure of PLCL/COL nanofibers in the inner layer (left), the PLGA/SF in the middle layer (middle), and randomly oriented PLCL/COL nanofibers in the external layer (right). c, d H&E (left) and Masson’s trichrome (right) staining images of transplanted grafts after 2 weeks and 10 weeks, respectively. Reprinted with permission from [126], Elsevier. e Cross-sectional SEM image of vascular grafts and relevant high magnification (right). f DAPI (right) and H&E staining (left) of bilayer scaffolds implanted in Sprague–Dawley rats after 16 weeks. Reproduced with the permission from [127], Elsevier