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. 2019 Nov 7;9:16212. doi: 10.1038/s41598-019-52667-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Discrimination and correlation of median-based PET-parameters. The vertical blue line is the median value of the PET parameter of interest. The horizontal pink lines are the median values of the metabolite of interest (here: threonine) in the two groups. The difference between the two horizontal pink lines is the effect size. The blue and pink dots represent the lung cancer patients of the low and high value groups, respectively.