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. 2019 Oct 16;48:70–80. doi: 10.1016/j.ebiom.2019.09.027

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 1 — FOXO3a is negatively correlated with the stemness of OSCC (a) Immunohistochemistry images of FOXO3a in pericarcinous epithelium (n = 124). The red line represents basement membrane. The layers from the red line to the green line represent the stratum basale. The layers from the green line to the orange line represent stratum spinosum. The layers from the orange line to the surface represent stratum granulosum/intermedium (b) Representative immunohistochemistry images of FOXO3a(left) and SOX2(right) expression in paraffin-embedded samples from OSCC tissue (n = 124) (c) The expression of FOXO3a in the side population of SCC15 and SCC25.