Table 2.
Univariate and multivariable Cox hazards analysis of the training cohort.
| Variables | Univariate |
Multivariate |
||
|---|---|---|---|---|
| HR(95% CI) | P-value | AHR(95% CI) | P-value | |
| Statistically significant factors | ||||
| WHO | ||||
| Ⅰ | Ref | Ref | Ref | Ref |
| Ⅱ | 1.442(0.680,3.059) | 0.340 | 1.376(0.569,3.330) | 0.478 |
| Ⅲ | 2.698(1.675,4.348) | <0.001 | 1.596(0.944,2.698) | 0.081 |
| Ⅳ | 5.113(2.977,8.782) | <0.001 | 1.870(0.997,3.507) | 0.051 |
| Disease stage (HIV) | 0.109(0.055,0.216) | <0.001 | 0.832(0.331,2.094) | 0.697 |
| Origin of identification | ||||
| Hospital | Ref | Ref | Ref | Ref |
| CDC | 0.407(0.234,0.706) | 0.001 | 0.648(0.354,1.185) | 0.159 |
| Others | 0.461(0.231,0.919) | 0.028 | 0.577(0.256,1.305) | 0.187 |
| CD4+ T-lymphocyte count, cells/μL | 0.990(0.988,0.992) | <0.001 | 0.995(0.992,0.999) | 0.007 |
| CD8+ T-lymphocyte count, cells/μL | 0.999(0.998,0.999) | <0.001 | 1.000(0.999,1.000) | 0.134 |
| Viral load, copies/mL | 4.882(3.881,6.142) | <0.001 | 4.025(3.029,5.348) | <0.001 |
| Platelet, 109/L | 1.003(1.001,1.005) | 0.006 | 1.001(0.998,1.004) | 0.412 |
| Haemoglobin, g/L | 0.970(0.963,0.978) | <0.001 | 0.988(0.979,0.998) | 0.014 |
| Aspartate transaminase, U/L | 1.005(1.002,1.009) | 0.004 | 0.993(0.984,1.003) | 0.159 |
| Body mass index, kg/m2 | 0.893(0.837,0.952) | 0.001 | 1.019(0.950,1.094) | 0.593 |
| Total cholesterol, mmol/L | 0.547(0.440,0.681) | <0.001 | 1.006(0.794,1.273) | 0.964 |
| Total bilirubin, μmol/L | 1.010(1.001,1.019) | 0.031 | 1.018(0.998,1.038) | 0.077 |
| Fasting plasma glucose, mmol/L | 1.021(1.003,1.040) | 0.023 | 1.064(1.027,1.101) | <0.001 |
| Statistically non-significant factors | ||||
| Woman | 0.947(0.564,1.592) | 0.838 | ||
| Age | 0.997(0.985,1.008) | 0.591 | ||
| TB | 1.686(0.848,3.353) | 0.136 | 2.115(0.944,4.738) | 0.069 |
| HBV(Negative) | 0.819(0.449,1.494) | 0.514 | ||
| Infection pathway | ||||
| NMHR | Ref | Ref | Ref | Ref |
| MSM | 0.530(0.323,0.869) | 0.012 | 1.046(0.581,1.883) | 0.881 |
| Others | 0.728(0.395,1.341) | 0.309 | 0.688(0.337,1.403) | 0.303 |
| Occupation | 0.941(0.828,1.070) | 0.356 | ||
| Farmer | Ref | Ref | Ref | Ref |
| Business people | 0.308(0.142,0.669) | 0.003 | 0.385(0.157,0.941) | 0.036 |
| House keeping | 0.881(0.514,1.510) | 0.645 | 1.807(1.002,3.259) | 0.049 |
| Worker | 0.909(0.492,1.681) | 0.762 | 1.224(0.625,2.398) | 0.556 |
| Others | 1.039(0.623,1.735) | 0.882 | 0.901(0.508,1.596) | 0.721 |
| History STD | 0.761(0.434,1.335) | 0.341 | ||
| Participants category | 0.998(0.644,1.548) | 0.993 | ||
| Education | 1.052(0.909,1.218) | 0.495 | ||
| Illiterate or elementary school | Ref | Ref | ||
| Senior middle school | 0.631(0.269,1.480) | 0.290 | ||
| Junior high school | 0.915(0.517,1.619) | 0.760 | ||
| College and above | 1.011(0.656,1.557) | 0.962 | ||
| Marital status | 1.369(0.932,2.011) | 0.110 | 0.764(0.483,1.209) | 0.250 |
| White blood cell, 109/L | 0.992(0.924,1.065) | 0.831 | ||
| Creatinine, μmol/L | 1.009(0.998,1.019) | 0.102 | 1.013(1.002,1.024) | 0.023 |
| Alanine aminotransferase, U/L | 1.003(0.998,1.007) | 0.235 | ||
| Triglyceride, mmol/L | 1.024(0.890,1.179) | 0.738 | ||
Abbreviations: NMHR, Non-marital heterosexual transmission; MSM, men who have sex with men; CDC, center for disease prevention and control; STD, sexually transmitted disease.