ALP |
alkaline phosphatase |
α-SMA |
alpha smooth muscle actin |
BDL |
bile duct ligation |
CCL4
|
carbon tetrachloride |
CK-19 |
cytokeratin-19 |
Col1a1 |
collagen, type I, alpha 1 |
DAPI |
4′,6-diamidino-2-phenylindole |
EMT |
epithelial to mesenchymal transition |
Fn1 |
fibronectin 1 |
GAPDH |
glyceraldehyde-3-phosphate dehydrogenase |
H&E |
hematoxylin & eosin |
HSCs |
hepatic stellate cells |
HHSteCs |
human hepatic stellate cell lines |
HIBEpiC |
human intrahepatic biliary epithelial cells |
HNF4α |
Hepatocyte nuclear factor 4 alpha |
hPSCL |
human PSC patient-derived cholangiocytes |
IBDM |
intrahepatic Bile Duct Mass |
Mdr2−/−
|
multidrug resistance gene 2 knockout |
p16 |
cyclin dependent kinase inhibitor 2A |
p21 |
cyclin-dependent kinase inhibitor 1 |
PSC |
primary sclerosing cholangitis |
S100a4 |
fibroblast-specific protein-1 |
SA-β-gal |
senescence associated β galactosidase |
SGOT |
serum glutamic oxaloacetic |
SGPT |
alanine aminotransferase |
TGF-β1 |
transforming growth factor-β1 |
VEGFA |
vascular endothelial growth factor A; |
WT |
wild-type |