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. 2019 Oct 15;48:341–352. doi: 10.1016/j.ebiom.2019.09.038

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Crown Copyright © 2019 Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Genomic organization of the IDO1 gene. Shown is the IDO1 transcript ENST00000518237.6, CG-density, target sites of HumanMethylation450 BeadChip beads, and the target sequence of the quantitative real-time PCR assay. The modified illustration was exported from www.ensemble.org (Version 89.38) and is based on Genome Reference Consortium Human Build 38 patch release 10 (GRCh38.p10). cg10262052 (bead 1) targets the central promoter site, bead cg08465774 (bead 2) probes the intragenic promoter flank, and bead cg24188163 (bead 3) targets the gene body.