Table 2.

Univariate and multivariate Cox regression analysis of circPICALM expression and survival of BC patients.

Characteristics	Univariate analysis		P-value	Multivariate analysis		P-value
	HR	95%CI		HR	95%CI
Gender	0.734	0.382–1.410	0.353
Age	1.024	0.999–1.049	0.061
Tumour size	0.858	0.403–1.825	0.691
Pathology stage	2.264	1.260–4.068	0.006⁎⁎	1.435	0.761–2.704	0.264
Grade	3.783	1.483–9.649	0.005⁎⁎	1.517	0.547–4.208	0.423
Lymphatic metastasis	4.026	2.253–7.194	0.000⁎⁎	2.034	1.043–3.963	0.042⁎
circPICALM expression	0.274	0.150–0.501	0.000⁎⁎	0.443	0.234–0.841	0.013⁎

Abbreviations: HR hazard ratio, CI confidence interval. Cox regression analysis.

^⁎P < .05.

^⁎⁎P < .01.