SWELL1 protects HCC cells from apoptosis. (a) Representative images of Hoechst 33258 staining in SMMC-7721, Huh7, Sk-hep-1, and HCCLM3 cells. (b) Results of Annexin V and PI staining by flow cytometry. (c) Representative images of the TUNEL assay. *P < .05, **P < .01. Data are represented as the mean ± SD of three independent experiments and compared using Student's t-test (Sk-hep-1 and HCCLM3 cells), or one-way ANOVA followed by a Dunnett t-test (SMMC-7721 and Huh7 cells).