Fig. 5.

Effect of SWELL1 on the levels of ROS, MMP, and intracellular ATP. (a) Results of the measurement of ROS in SMMC-7721, Huh7, Sk-hep-1, and HCCLM3 cells by fluorescence microscope and flow cytometry. (b) Results of the MMP measurement by flow cytometry. The ratio of red/green fluorescence intensity was defined as the changes in MMP in HCC cells. (c) Results of intracellular ATP content. *P < .05, **P < .01. Data are represented as the mean ± SD of three independent experiments and compared using Student's t-test (Sk-hep-1 and HCCLM3 cells), or one-way ANOVA followed by a Dunnett t-test (SMMC-7721 and Huh7 cells). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)